International Chemical Safety Cards 2-AMINOPYRIDINE ICSC: 0214 2-AMINOPYRIDINE o-Aminopyridine alpha-Aminopyridine 2-Pyridylamine C5N2H6/NH2C5H4N Molecular mass: 94.1 CAS # 504-29-0 RTECS # US1575000 ICSC # 0214 UN # 2671 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR! INHALATION Convulsions. Dizziness. Headache. Nausea. Shortness of breath. Weakness. Increased blood pressure. Collapse. Local exhaust or breathing protection. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention. SKIN MAY BE ABSORBED! Redness (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES Redness. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION (further see Inhalation). Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place (extra personal protection: P3 filter respirator for toxic particles). Separated from strong oxidants, food and feedstuffs. Dry. Airtight. Do not transport with food and feedstuffs. UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0214 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards 2-AMINOPYRIDINE ICSC: 0214 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS OR WHITE POWDER OR CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. CHEMICAL DANGERS: The substance decomposes on burning producing toxic gases and vapours including nitrous oxides. Reacts with strong oxidants causing fire and explosion hazard. The substance is a strong base that is soluble in water. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 0.5 ppm; 1.9 mg/m3 (as TWA) (ACGIH 1993-1994). OSHA PEL: TWA 0.5 ppm (2 mg/m3) NIOSH REL: TWA 0.5 ppm (2 mg/m3) NIOSH IDLH: 5 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and through the skin. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system , resulting in convulsions, respiratory failure. Exposure may result in death. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 211°C Melting point: 58°C Relative density (water = 1): see Notes Solubility in water: very good Vapour pressure, kPa at 20°C: about 0.13 Relative vapour density (air = 1): 3.2 Flash point: 68°C c.c. Octanol/water partition coefficient as log Pow: 0.49 ENVIRONMENTAL DATA N O T E S Relative density and auto-ignition temperature are unknown in literature. Combustible solid whose vapours can form explosive mixtures with air at elevated temperatures. The relation between odour and the occupational exposure limit cannot be indicated. Do NOT take working clothes home. Transport Emergency Card: TEC (R)-61G12b ADDITIONAL INFORMATION ICSC: 0214 2-AMINOPYRIDINE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.