International Chemical Safety Cards

o-ANISIDINE ICSC: 0970

o-ANISIDINE
2-Methoxybenzenamine
2-Methoxyaniline
2-Aminoanisole
C7H9NO/H2NC6H4OCH3
Molecular mass: 123.16
CAS # 90-04-0
RTECS # BZ5410000
ICSC # 0970
UN # 2431
EC # 612-035-00-4
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION


EXPOSURE
STRICT HYGIENE!
IN ALL CASES CONSULT A DOCTOR!
  • INHALATION
    		• Blue lips or finger nails. Blue skin. Dizziness. Drowsiness. Headache. Nausea. Vomiting.
    		Local exhaust or breathing protection.
    		Fresh air, rest. Refer for medical attention.
  • SKIN
    		• MAY BE ABSORBED! (further see Inhalation).
    		Protective gloves. Protective clothing.
    		Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
  • EYES

    		• Face shield or eye protection in combination with breathing protection.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• (further see Inhalation).
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. Give large quantities of water immediately. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: P2 filter respirator for harmful particles).
    		Separated from strong oxidants, acids, food and feedstuffs, acid chlorides, acid anhydrides and chloroformates. Cool. Dry. Keep in the dark. Well closed.
    		Airtight. Do not transport with food and feedstuffs.
    T+ symbol
    R: 26/27/28-33
    S: 28-36/37-45
    UN Hazard Class: 6.1
    UN Packing Group: III
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0970 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    o-ANISIDINE ICSC: 0970

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    PHYSICAL STATE; APPEARANCE:
     YELLOWISH LIQUID , WITH CHARACTERISTIC ODOUR. TURNS BROWNISH ON EXPOSURE TO AIR.

    PHYSICAL DANGERS:

    CHEMICAL DANGERS:
     The substance decomposes on heating producing toxic fumes (nitrogen oxides). Reacts with strong oxidants causing fire and explosion hazard. Reacts with acids, acid chlorides, acid anydrides, chloroformates. Attacks some forms of plastics, rubber and coatings.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
     TLV: 0.1 ppm; 0.50 mg/m3 (skin) (ACGIH 1991-1992).
    PDK: 1 mg/m3 (USSR 1970).
    OSHA PEL: TWA 0.5 mg/m3 skin
    NIOSH REL: Ca 0.5 mg/m3 skin See Appendix A
    NIOSH IDLH: Potential occupational carcinogen 50 mg/m3


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

    INHALATION RISK:
     A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance may cause effects on the blood , resulting in cyanosis, formation of methaemoglobin. Medical observation is indicated.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     The substance may have effects on the blood , resulting in forming of methaemoglobin. This substance is possibly carcinogenic to humans.
    PHYSICAL
    PROPERTIES
    Boiling point: 225°C
    Melting point: 5°C
    Relative density (water = 1): 1.092
    Solubility in water: poor
    		 Vapour pressure, kPa at 30°C: <0.133
    Relative vapour density (air = 1): 4.25
    Flash point: 118°C
    Octanol/water partition coefficient as log Pow: 0.95
    ENVIRONMENTAL
    DATA
    NOTES
    The compound is volatile with steam. Depending on the degree of exposure, periodic medical examination is indicated. Do NOT take working clothes home.
    NFPA Code: H 2; F 1; R 0;
    ADDITIONAL INFORMATION


    ICSC: 0970 o-ANISIDINE
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.