International Chemical Safety Cards BENZYL CHLORIDE ICSC: 0016 BENZYL CHLORIDE alpha-Chlorotoluene (Chloromethyl)benzene Tolyl chloride C7H7Cl/C6H5CH2Cl Molecular mass: 126.6 CAS # 100-44-7 RTECS # XS8925000 ICSC # 0016 UN # 1738 EC # 602-037-00-3 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, AFFF, foam, carbon dioxide. EXPLOSION Above 67°C explosive vapour/air mixtures may be formed. Above 67°C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN! INHALATION Burning sensation. Cough. Nausea. Headache. Shortness of breath. Dizziness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Refer for medical attention. SKIN MAY BE ABSORBED! Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Redness. Pain. Blurred vision. Severe deep burns. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal pain. Diarrhoea. Vomiting. Burning sensation behind the breastbone. Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking liquid in covered non-metallic containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from food and feedstuffs, and incompatible materials: see chemical dangers. Dry. Ventilation along the floor. Store only if stabilized. Do not transport with food and feedstuffs. Xi symbol R: 36/37/38 S: 39 UN Hazard Class: 6.1 UN Subsidiary Risks: 8 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0016 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards BENZYL CHLORIDE ICSC: 0016 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance will polymerize under the influence of all common metals except nickel and lead, with evolution of corrosive fumes (hydrogen chloride - see ICSC # 0163), with fire or explosion hazard. On combustion, forms toxic and corrosive fumes (hydrogen chloride). Reacts vigorously with strong oxidants. Reacts with water, producing corrosive fumes (hydrogen chloride - see ICSC # 0163). Attacks many metals in presence of water. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 1 ppm; 5.2 mg/m3 (as TWA) (ACGIH 1992-1993). OSHA PEL: TWA 1 ppm (5 mg/m3) NIOSH REL: C 1 ppm (5 mg/m3) 15-minute NIOSH IDLH: 10 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and through the skin. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C; on spraying much faster. EFFECTS OF SHORT-TERM EXPOSURE: Tear drawing. The substance is corrosive to the eyes. The vapour irritates the eyes, the skin and the respiratory tract. Inhalation of the vapour or aerosol may cause lung oedema (see Notes). The substance may cause effects on the central nervous system , resulting in unconsciousness. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver and kidneys , resulting in severe damage. Tumours have been detected in experimental animals but may not be relevant to humans (see Notes). Animal tests show that this substance possibly causes toxic effects upon human reproduction. PHYSICAL PROPERTIES Boiling point: 179°C Melting point: about -43°C Relative density (water = 1): 1.1 Solubility in water: none (<0.1 g/100 ml) Vapour pressure, Pa at 20°C: 120 Relative vapour density (air = 1): 4.4 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 67°C (c.c.)°C Auto-ignition temperature: 585°C Explosive limits, vol% in air: 1.1-14.0 Octanol/water partition coefficient as log Pow: 2.3 ENVIRONMENTAL DATA NOTES Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. The odour warning when the exposure limit value is exceeded is insufficient. Transport Emergency Card: TEC (R)-772 NFPA Code: H2; F2; R1; ADDITIONAL INFORMATION ICSC: 0016 BENZYL CHLORIDE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.