International Chemical Safety Cards

1,2-DICHLOROPROPANE ICSC: 0441

1,2-DICHLOROPROPANE
Propylene dichloride
C3H6Cl2
Molecular mass: 113.0
CAS # 78-87-5
RTECS # TX9625000
ICSC # 0441
UN # 1279
EC # 602-020-00-0
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Highly flammable.
NO open flames, NO sparks, and NO smoking.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID ALL CONTACT!

  • INHALATION
    		• Anorexia, diarrhoea, drowsiness, headache, sore throat. Symptoms may be delayed (see Notes).
    		Ventilation, local exhaust, or breathing protection.
    		Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
  • SKIN
    		• Dry skin, redness, pain.
    		Protective gloves.
    		First rinse with plenty of water, then remove contaminated clothes and rinse again. Refer for medical attention.
  • EYES
    		• Redness, pain.
    		Safety goggles.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Abdominal pain, diarrhoea, drowsiness, headache, nausea, vomiting.
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: self-contained breathing apparatus).
    		Fireproof. Provision to contain effluent from fire extinguishing. Separated from bases, strong oxidants, acids.

    F symbol
    Xn symbol
    R: 11-20
    S: 9-16-29-33
    UN Hazard Class: 3
    UN Packing Group: II (M)
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0441 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    1,2-DICHLOROPROPANE ICSC: 0441

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    PHYSICAL STATE; APPEARANCE:
     COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

    PHYSICAL DANGERS:
     The vapour is heavier than air and may travel along the ground; distant ignition possible.

    CHEMICAL DANGERS:
     On combustion, forms toxic and corrosive fumes and gases (hydrogen chloride - see ICSC # 0163 and phosgene - see ICSC # 0007). Reacts violently with strong oxidants, acids, and bases, causing fire and explosion hazard. Corrosive to aluminum alloys.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
     TLV: 75 ppm; 347 mg/m3 (as TWA); 110 ppm; 508 mg/m3 (as STEL) (ACGIH 1991-1992).
    PDK: 10 mg/m3 (as CEILING) (USSR 1977).
    OSHA PEL: TWA 75 ppm (350 mg/m3)
    NIOSH REL: Ca See Appendix A
    NIOSH IDLH: Potential occupational carcinogen 400 ppm


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation and through the skin, and by ingestion.

    INHALATION RISK:
     A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance irritates the eyes, the skin, and the respiratory tract. The substance may cause effects on the nervous system. Exposure to high concentrations may result in unconsciousness.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and blood. Animal tests show that this substance possibly causes malformations in human babies.
    PHYSICAL
    PROPERTIES
    Boiling point: 96°C
    Melting point: -100°C
    Relative density (water = 1): 1.16
    Solubility in water, g/100 ml at 20°C: 0.26
    Vapour pressure, kPa at 20°C: 5.3
    Relative vapour density (air = 1): 3.9
    		 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.15
    Flash point: 16°C (c.c.)°C
    Auto-ignition temperature: 557°C
    Explosive limits, vol% in air: 3.4-14.5
    Octanol/water partition coefficient as log Pow: 2.02 (calculated)
    ENVIRONMENTAL
    DATA
    NOTES
    Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of inhalation exposure do not become manifest until more than 24 hours later.
    NFPA Code: H 2; F 3; R 0;
    ADDITIONAL INFORMATION


    ICSC: 0441 1,2-DICHLOROPROPANE
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.