International Chemical Safety Cards

ISOPHORONE ICSC: 0169

ISOPHORONE
1,1,3-Trimethyl-3-cyclohexene-5-one
3,5,5-Trimethyl-2-cyclohexene-1-one
Isoacetophorone
C9H14O
Molecular mass: 138.2
CAS # 78-59-1
RTECS # GW7700000
ICSC # 0169
EC # 606-012-00-8
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible.
NO open flames.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Above 84°C explosive vapour/air mixtures may be formed.
Above 84°C use a closed system, ventilation.

EXPOSURE
PREVENT GENERATION OF MISTS!

  • INHALATION
    		• Burning sensation. Cough. Dizziness. Headache. Nausea. Shortness of breath.
    		Ventilation, local exhaust, or breathing protection.
    		Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
  • SKIN
    		• Dry skin. Redness.
    		Protective gloves.
    		Remove contaminated clothes. Rinse and then wash skin with water and soap.
  • EYES
    		• Redness. Pain. Blurred vision.
    		Safety spectacles.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Abdominal pain. Burning sensation (further see Inhalation).
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place.
    		Separated from strong oxidants.

    Xi symbol
    R: 36/37/38
    S: (2-)26
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0169 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    ISOPHORONE ICSC: 0169

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    PHYSICAL STATE; APPEARANCE:
     COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

    PHYSICAL DANGERS:

    CHEMICAL DANGERS:
     Reacts with strong oxidants.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
     TLV: 5 ppm; 28 mg/m3 (ceiling values) (ACGIH 1993-1994).
    OSHA PEL: TWA 25 ppm (140 mg/m3)
    NIOSH REL: TWA 4 ppm (23 mg/m3)
    NIOSH IDLH: 200 ppm


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

    INHALATION RISK:
     A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance and the vapour of this substance irritates the eyes, the skin and the respiratory tract. Exposure could cause lowering of consciousness.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     Repeated or prolonged contact with skin may cause dermatitis. Lungs may be affected by inhalation of high concentrations. The substance may have effects on the liver and kidneys.
    PHYSICAL
    PROPERTIES
    Boiling point: 215°C
    Melting point: -8°C
    Relative density (water = 1): 0.92
    Solubility in water, g/100 ml at 25°C: 1.2
    Vapour pressure, Pa at 20°C: 40
    		 Relative vapour density (air = 1): 4.8
    Flash point: 84°C c.c.°C
    Auto-ignition temperature: 460°C
    Explosive limits, vol% in air: 0.8-3.8
    Octanol/water partition coefficient as log Pow: 2.2
    ENVIRONMENTAL
    DATA
    N O T E S
    The occupational exposure limit value should not be exceeded during any part of the working exposure. Depending on the degree of exposure, periodic medical examination is indicated.
    Transport Emergency Card: TEC (R)-621
    NFPA Code: H 2; F 2; R 0;
    ADDITIONAL INFORMATION


    ICSC: 0169 ISOPHORONE
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.